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human melanoma tissue microarray tma  (Novus Biologicals)


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    Novus Biologicals human melanoma tissue microarray tma
    Human Melanoma Tissue Microarray Tma, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 94/100, based on 19 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/human melanoma tissue microarray tma/product/Novus Biologicals
    Average 94 stars, based on 19 article reviews
    human melanoma tissue microarray tma - by Bioz Stars, 2026-05
    94/100 stars

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    Global changes in melanoma cells transcriptome following the knockdown (KD) of CCT3 . (A) Hierarchical cluster analysis of differentially expressed genes with fold change of > 2.0. Row and column represent gene and experimental cells, respectively. Upregulated and downregulated genes are shown in red and green, respectively. (B) Signaling enrichment analysis of CCT3-downregulated classical signaling pathways based on IPA. Differential data are presented as z-scores (based on Fold change). (C) The expression trends of molecules in cyclins and cell cycle regulation pathway (based on IPA). Red and green represent upregulated and downregulated genes, respectively. (D) Knowledge-based interaction network of CCT3 targets after comparing the CCT3-KD and the shCtrl cells. The network was built on the basis of the CCT3 interactome of microarray data with a 1.5-fold change cutoff. The intensity of the node color indicates the degree of upregulation (red) or downregulation (green). Light colors represent less significant p values.

    Journal: Journal of Cancer

    Article Title: Suppression of CCT3 inhibits melanoma cell proliferation by downregulating CDK1 expression

    doi: 10.7150/jca.69497

    Figure Lengend Snippet: Global changes in melanoma cells transcriptome following the knockdown (KD) of CCT3 . (A) Hierarchical cluster analysis of differentially expressed genes with fold change of > 2.0. Row and column represent gene and experimental cells, respectively. Upregulated and downregulated genes are shown in red and green, respectively. (B) Signaling enrichment analysis of CCT3-downregulated classical signaling pathways based on IPA. Differential data are presented as z-scores (based on Fold change). (C) The expression trends of molecules in cyclins and cell cycle regulation pathway (based on IPA). Red and green represent upregulated and downregulated genes, respectively. (D) Knowledge-based interaction network of CCT3 targets after comparing the CCT3-KD and the shCtrl cells. The network was built on the basis of the CCT3 interactome of microarray data with a 1.5-fold change cutoff. The intensity of the node color indicates the degree of upregulation (red) or downregulation (green). Light colors represent less significant p values.

    Article Snippet: A human melanoma tissue microarray (TMA-ME803a) that contains 40 patient samples was purchased from Genechem Co.,Ltd.

    Techniques: Knockdown, Protein-Protein interactions, Expressing, Microarray